{"id":40134,"date":"2024-08-08T16:14:54","date_gmt":"2024-08-08T20:14:54","guid":{"rendered":"https:\/\/www.vielight.com\/?p=40134"},"modified":"2025-07-28T11:11:33","modified_gmt":"2025-07-28T15:11:33","slug":"vielight-photobiomodulation-and-microtubulin-implications-for-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/www.vielight.com\/blog\/vielight-photobiomodulation-and-microtubulin-implications-for-alzheimers-disease\/","title":{"rendered":"Research on Microtubulin with Vielight technology | Implications for Alzheimer&#8217;s Disease"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container has-pattern-background has-mask-background nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-center fusion-flex-content-wrap\" style=\"max-width:1144px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_3 1_3 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-image-element awb-imageframe-style awb-imageframe-style-below awb-imageframe-style-1\" style=\"--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-none imageframe-1 hover-type-none\"><img decoding=\"async\" width=\"877\" height=\"1339\" title=\"brain-photobiomodulation-cell-effects\" src=\"https:\/\/www.vielight.com\/wp-content\/uploads\/2024\/08\/brain-photobiomodulation-cell-effects.jpg\" alt class=\"img-responsive wp-image-40166\" srcset=\"https:\/\/www.vielight.com\/wp-content\/uploads\/2024\/08\/brain-photobiomodulation-cell-effects-200x305.jpg 200w, https:\/\/www.vielight.com\/wp-content\/uploads\/2024\/08\/brain-photobiomodulation-cell-effects-400x611.jpg 400w, https:\/\/www.vielight.com\/wp-content\/uploads\/2024\/08\/brain-photobiomodulation-cell-effects-600x916.jpg 600w, https:\/\/www.vielight.com\/wp-content\/uploads\/2024\/08\/brain-photobiomodulation-cell-effects-800x1221.jpg 800w, https:\/\/www.vielight.com\/wp-content\/uploads\/2024\/08\/brain-photobiomodulation-cell-effects.jpg 877w\" sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 400px\" \/><\/span><div class=\"awb-imageframe-caption-container\" style=\"text-align:center;\"><div class=\"awb-imageframe-caption\"><h2 class=\"awb-imageframe-caption-title\"> <\/h2><p class=\"awb-imageframe-caption-text\">The effects of 810nm energy from the Vielight Neuro on microtubulin<\/p><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_2_3 2_3 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:66.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:2.88%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:2.88%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-1\"><p class=\"cvGsUA direction-ltr align-start para-style-body\"><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">This new <\/span><a class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-underline text-strikethrough-none\" draggable=\"false\" href=\"https:\/\/www.mdpi.com\/2079-4991\/14\/13\/1093\" target=\"_blank\" rel=\"noopener\"><strong>groundbreaking study<\/strong><\/a><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\"> with Vielight technology conducted in partnership with the Department of Mechanical and Aerospace Engineering University of Turin and the University of Alberta explores the effects of 810nm NIR energy on crucial cellular structures known as tubulin.<\/span><\/p>\n<p class=\"cvGsUA direction-ltr align-start para-style-body\"><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Healthy cellular function and structure are intrinsically linked to the integrity of tubulins. Tubulins are proteins found in all eukaryotic cells and play a critical role in their structure and function. Eukaryotic cells typically contain 3\u20134% tubulin. <\/span><span style=\"text-decoration: underline;\"><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-strikethrough-none text-decoration-underline\">Notably, however, mammalian brain tissue is particularly rich in tubulin content, consisting of 10% or more of the total protein content.<\/span><\/span><\/p>\n<p class=\"cvGsUA direction-ltr align-start para-style-body\"><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Tubulin, crucial in Alzheimer&#8217;s pathology, was studied for PBM&#8217;s effects using Raman spectroscopy. Tubulin samples exposed to pulsed NIR radiation with Vielight LED technology (810 nm, 10 Hz, 22.5 J\/cm\u00b2) revealed significant changes in protein structures.<\/span><\/p>\n<p class=\"cvGsUA direction-ltr align-start para-style-body\"><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Using this validated imaging method, statistically significant alterations in the secondary structures of polymerized NIR-exposed tubulin were observed, characterized by a notable decrease in \u03b1-helix content and a concurrent increase in \u03b2-sheets compared to the control samples.<\/span><\/p>\n<p class=\"cvGsUA direction-ltr align-start para-style-body\"><span style=\"text-decoration: underline;\"><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-underline text-strikethrough-none\">This newly discovered mechanism with Vielight technology could have implications for reducing the risks associated with brain aging, including neurodegenerative diseases like Alzheimer\u2019s disease, through the introduction of an intervention following this transition. and potential for brain aging intervention.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":40135,"comment_status":"closed","ping_status":"closed","sticky":true,"template":"","format":"standard","meta":{"_acf_changed":false,"bwfblock_default_font":"","inline_featured_image":false,"mc4wp_mailchimp_campaign":[],"footnotes":""},"categories":[3012,476,2997,475],"tags":[],"class_list":["post-40134","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-alzheimers","category-infrared-light-therapy","category-longevity-anti-aging-technology-for-the-elderly","category-photobiomodulation"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.vielight.com\/wp-json\/wp\/v2\/posts\/40134","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vielight.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vielight.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vielight.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vielight.com\/wp-json\/wp\/v2\/comments?post=40134"}],"version-history":[{"count":0,"href":"https:\/\/www.vielight.com\/wp-json\/wp\/v2\/posts\/40134\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vielight.com\/wp-json\/wp\/v2\/media\/40135"}],"wp:attachment":[{"href":"https:\/\/www.vielight.com\/wp-json\/wp\/v2\/media?parent=40134"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vielight.com\/wp-json\/wp\/v2\/categories?post=40134"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vielight.com\/wp-json\/wp\/v2\/tags?post=40134"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}